The reserve is situated at the extreme south of Costa Rica, along the well-named Paradise Road, connecting Punta Uva to the Talamanca valley. It winds between the Costa Rican jungle and the green fields that are surprisingly close to the beaches of Manzanillo (elected the most beautiful beach in Costa Rica by the 2011 Lonely Planet guide), Punta Uva, Playa Chiquita and Cocles. The closest town, at about 15 minutes by car, is Puerto Viejo de Talamanca, a symbol to the "Pura Vida" way of life.

You can find banks, pharmacies, supermarkets and nightlife. Everything here is so different that it gives the visitor the impression of being at the end of the world. Accessibility to the region has become easier due to the progress made in the last few years. Its relative distance allows one to take advantage of the scenery while preserving the tranquility of the area. It is not an area of mass tourism, however a wide variety of accommodations are available combining both quality and authenticity.